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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Pediatr+Rheumatol+Online+J
2016 ; 14
(1
): 33
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Ultrasound in juvenile idiopathic arthritis
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Magni-Manzoni S
Pediatr Rheumatol Online J
2016[May]; 14
(1
): 33
PMID27234966
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BACKGROUND: In the recent years, musculoskeletal ultrasound (MSUS) has been
regarded as especially promising in the assessment of juvenile idiopathic
arthritis (JIA), as a reliable method to precisely document and monitor the
synovial inflammation process. MAIN CONTENT: MSUS is particularly suited for
examination of joints in children due to several advantages over other imaging
modalities. Some challenges should be considered for correct interpretation of
MSUS findings in children, due to the peculiar features of the growing skeleton.
MSUS in JIA is considered particularly useful for its ability to detect
subclinical synovitis, to improve the classification of patients in JIA subtypes,
for the definition of remission, as guidance to intraarticular corticosteroid
injections and for capturing early articular damage. Current evidence and
applications of MSUS in JIA are documented by several authors. Recent advances
and insights into further investigations on MSUS in healthy children and in JIA
patients are presented and discussed in the present review. CONCLUSIONS: MSUS
shows great promise in the assessment and management of children with JIA.
Nonetheless, anatomical knowledge of sonographic changes over time, underlying
immunopathophysiology, standardization and validation of MSUS in healthy children
and in patients with JIA are still under investigation. Further research and
educational efforts are required for expanding this imaging modality to more
clinicians in their daily practice.
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