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2018 ; 10
(ä): 189-191
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Two cases of cytomegalovirus panuveitis in immunocompetent patients
#MMPMID29780935
Sakai M
; Takase H
; Namba K
; Mizuuchi K
; Iwata D
; Ishida S
Am J Ophthalmol Case Rep
2018[Jun]; 10
(ä): 189-191
PMID29780935
show ga
PURPOSE: To report two cases of panuveitis in immunocompetent patients in which
cytomegalovirus was involved. OBSERVATION: Case 1 was a 46-year-old man who had a
history of recurrent anterior chamber inflammations in his left eye. After Nd:YAG
laser posterior capsulotomy, he developed panuveitis with vitreous haze and
periphlebitis. Polymerase chain reaction (PCR) examination revealed the presence
of cytomegalovirus (CMV) DNA in the anterior chamber (AC). He responded well to a
series of intravitreal injections of ganciclovir (GCV). Case 2 was a 63-year-old
woman who had a history of recurrent anterior uveitis in her left eye. Two years
after cataract surgery, AC inflammation, diffuse vitreous haze, and periphlebitis
had developed. CMV DNA was detected in the AC. Intravitreal injections of GCV and
oral valganciclovir were administered, and ocular inflammation finally improved.
CONCLUSIONS: and importance: We experienced two cases of CMV panuveitis in
immunocompetent adults, both of which responded well to anti-viral therapies.