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2016 ; 2016
(ä): 160016
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Turner syndrome: don t forget the vulva
#MMPMID27252865
Haidopoulos D
; Bakolas G
; Michala L
Endocrinol Diabetes Metab Case Rep
2016[]; 2016
(ä): 160016
PMID27252865
show ga
Turner syndrome (TS) has been linked to a number of autoimmune conditions,
including lichen sclerosus (LS), at an estimated prevalence of 17%. LS is a known
precursor to vulvar cancer. We present a case of vulvar cancer in a 44-year-old
woman, who had previously complained of pruritus in the area, a known symptom of
LS. Histology confirmed a squamous cell carcinoma with underlying LS. Vulvar
assessment for the presence of LS should be undertaken regularly as part of the
routine assessments proposed for adult TS women. If LS is identified, then the
patient should be warned of the increased risk of vulvar cancer progression and
should be monitored closely for signs of the condition. LEARNING POINTS: Patients
with TS are at increased risk of developing LS.LS is a known precursor to vulvar
cancer.TS women with LS may be at risk of developing vulvar cancer and should be
offered annual vulvar screening and also be aware of signs and symptoms of early
vulvar cancer.