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10.1021/ml300284b

http://scihub22266oqcxt.onion/10.1021/ml300284b
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C4027432!4027432 !24900566
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suck abstract from ncbi


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pmid24900566
      ACS+Med+Chem+Lett 2013 ; 4 (1 ): 75-8
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  • Tuning RNA Interference by Enhancing siRNA/PAZ Recognition #MMPMID24900566
  • Gaglione M ; Potenza N ; Di Fabio G ; Romanucci V ; Mosca N ; Russo A ; Novellino E ; Cosconati S ; Messere A
  • ACS Med Chem Lett 2013[Jan]; 4 (1 ): 75-8 PMID24900566 show ga
  • Chemically modified siRNAs were synthesized to enhance the corresponding silencing activities. The introduced modifications endowed siRNAs with high silencing effect, long RNAi persistence, and better serum resistance. Theoretical data allowed us to correlate the observed siRNAs interfering performance with the peculiar interactions with PAZ.
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