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10.1080/2162402X.2015.1086862 http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1086862 C4839364!4839364 !27141343     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27141343 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Oncoimmunology 2016 ; 5 (3 ): e1086862 Nephropedia Template TP {{tp|p=27141343 |t=2016. Tumor-intrinsic oncogene pathways mediating immune avoidance |pdf=|usr=}}{{27141343 }} gab.com Text Tumor-intrinsic oncogene pathways mediating immune avoidance JO: Oncoimmunology http://www.kidney.de/pget.php?&tw=1&pmid=27141343 #FOAvip Immunotherapy is emerging as a major treatment for patients with cancer, predominantly via blocking immune inhibitory pathways and through adoptive T cell therapy. However, only a subset of patients shows clinical responses to these interventions. Emerging data indicates a correlation between clinical response and a pre-existing T cell-inflamed tumor microenvironment. Tumor-intrinsic ?-catenin activation has been identified as mediating exclusion of T cells from the tumor microenvironment and other oncogene pathways are being explored similarly. Understanding the molecular mechanisms underlying immune avoidance should identify new therapeutic targets for expanding efficacy of immunotherapies. Twit Text FOAVip Tumor-intrinsic oncogene pathways mediating immune avoidance ????Oncoimmunology http://www.kidney.de/pget.php?&tw=1&pmid=27141343 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27141343 #FOAvip English Wikipedia <ref>{{Cite pmid|27141343 }}</ref> Tumor-intrinsic oncogene pathways mediating immune avoidance #MMPMID27141343 Spranger S ; Gajewski TF Oncoimmunology 2016[Mar]; 5 (3 ): e1086862 PMID27141343 show ga Immunotherapy is emerging as a major treatment for patients with cancer, predominantly via blocking immune inhibitory pathways and through adoptive T cell therapy. However, only a subset of patients shows clinical responses to these interventions. Emerging data indicates a correlation between clinical response and a pre-existing T cell-inflamed tumor microenvironment. Tumor-intrinsic ?-catenin activation has been identified as mediating exclusion of T cells from the tumor microenvironment and other oncogene pathways are being explored similarly. Understanding the molecular mechanisms underlying immune avoidance should identify new therapeutic targets for expanding efficacy of immunotherapies. ?Tumor-intrinsic oncogene pathways mediating immune avoidance (epmc).pdf DeepDyve Pubget Overpricing