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2016 ; 22
(11
): 921-924
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Tuft Cells: New Players in Colitis
#MMPMID27717671
Steele SP
; Melchor SJ
; Petri WA Jr
Trends Mol Med
2016[Nov]; 22
(11
): 921-924
PMID27717671
show ga
A recent surge of interest in tuft cells, which are chemosensory intestinal
epithelial cells, has uncovered new functional roles for these cells in
colorectal cancer, metabolic signaling, and type 2 immunity. Here, we explore
emerging evidence suggesting that tuft cells are critical for protection during
enteric infections and inflammatory responses.