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2015 ; 28
(5
): 408-16
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Tropical and travel-associated norovirus: current concepts
#MMPMID26237546
Ballard SB
; Saito M
; Mirelman AJ
; Bern C
; Gilman RH
Curr Opin Infect Dis
2015[Oct]; 28
(5
): 408-16
PMID26237546
show ga
PURPOSE OF REVIEW: We highlight recent advances relevant to understanding
norovirus infections in the tropics, both in populations living in developing
settings and travelers to these regions. RECENT FINDINGS: Because of the decrease
in diarrheal disease associated with the global rollout of vaccines against
rotavirus, norovirus is emerging as the predominant cause of diarrhea morbidity
among children in the tropics, and evidence suggests that it contributes to adult
disease in endemic populations and travelers. In addition to identifying
potential target populations for preventive measures, we provide an update on
norovirus vaccine development and concepts related to their implementation in
low-income and middle-income countries. SUMMARY: These current concepts related
to norovirus-attributable disease burden, clinical significance, and economic
impact can potentially be applied to tailoring efforts to prevent and mitigate
the effects of this important enteropathogen.