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2017 ; 2
(5
): 110-116
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Treatment of chronic orthopaedic infection
#MMPMID28630748
Winkler H
EFORT Open Rev
2017[May]; 2
(5
): 110-116
PMID28630748
show ga
Chronic infections are one of the major challenges in orthopaedic surgery, both
for surgeons and patients. They are characterised by obstinate persistency of the
causing microorganisms and resulting long-term disablement of the patients,
associated with remarkable costs for the health care system.Difficulties derive
from the biofilm-mode of living of pathogens with resistances against
immunological defence and antimicrobial substances, and osseous defects resulting
from the disease itself and surgical interventions.Established techniques usually
require multiple costly operations with extended periods of disablement and
impairment of the patients, sometimes making the therapy worse than the
disease.Better understanding of the backgrounds of the conditions has led to new
surgical techniques and differentiated application of antibiotics, aiming in
improved quality of life for our patients. Cite this article: EFORT Open Rev
2017;2. DOI: 10.1302/2058-5241.2.160063. Originally published online at
www.efortopenreviews.org.
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