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Treatment of Adult Soft Tissue Sarcomas: An Overview
#MMPMID27182479
Arifi S
; Belbaraka R
; Rahhali R
; Ismaili N
Rare Cancers Ther
2015[]; 3
(1
): 69-87
PMID27182479
show ga
Sarcomas are uncommon malignancies accounting for about 1% of all adult
malignancies. Sarcomas are a heterogeneous group of tumors which includes more
than 100 different subtypes. Surgery is the mainstay therapy for localized
disease. In selected patients the combination of surgery with radiotherapy
achieves better local control and offers the best chance of cure. Systemic
treatment including cytotoxic chemotherapy or targeted therapies remains the
mainstay therapy for most patients with advanced disease. There are a wide
variety of clinical situations, such that an individualized treatment plan must
be defined by a multidisciplinary tumor board. Treatment decisions should take
into consideration the histology, site of disease, stage, performance status,
treatment goals, and the patient's wishes. The management of patients should be
carried out in a center with expertise in the treatment of sarcomas for optimal
outcome. This review will cover the different treatment modalities of adult soft
tissue sarcomas.
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