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2015 ; 68
(2
): 101-5
Nephropedia Template TP
Korean J Anesthesiol
2015[Apr]; 68
(2
): 101-5
PMID25844126
show ga
Transfusion-related acute lung injury (TRALI) was introduced in 1983 to describe
a clinical syndrome seen within 6 h of a plasma-containing blood products
transfusion. TRALI is a rare transfusion complication; however, the FDA has
suggested that TRALI is the leading cause of transfusion-related mortality.
Understanding the pathogenesis of TRALI will facilitate adopting preventive
strategies, such as deferring high plasma volume female product donors. This
review outlines the clinical features, pathogenesis, treatment, and prevention of
TRALI.