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10.1089/cell.2014.0089 http://scihub22266oqcxt.onion/10.1089/cell.2014.0089 C4487681!4487681 !26053515     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26053515 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26053515 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Reprogram 2015 ; 17 (3 ): 151-9 Nephropedia Template TP {{tp|p=26053515 |t=2015. Transdifferentiation of Fibroblasts by Defined Factors |pdf=|usr=}}{{26053515 }} gab.com Text Transdifferentiation of Fibroblasts by Defined Factors JO: Cell Reprogram http://www.kidney.de/pget.php?&tw=1&pmid=26053515 #FOAvip Cellular differentiation is usually considered to be an irreversible process during development due to robust lineage commitment. Feedback and feed-forward loops play a significant role in maintaining lineage-specific gene expression processes in various cell types, and, in turn, factors secreted by cells may regulate the homeostatic balance of these cycles during development and differentiation. The output of biological responses is controlled by such mechanisms in many regulatory pathways through gene networks involved in transcription, RNA metabolism, signal transduction, micromolecular synthesis, and degradation. The pluripotent stage during cellular conversion may be avoided through ectopic expression of lineage-specific factors. Lineage-specific transcription factors produced during development may strengthen cell type-specific gene expression patterns. Cellular phenotypes are further stabilized by epigenetic modifications. This reprogramming approach could have important implications for disease modeling and regenerative and personalized medicine. Twit Text FOAVip Transdifferentiation of Fibroblasts by Defined Factors ????Cell Reprogram http://www.kidney.de/pget.php?&tw=1&pmid=26053515 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26053515 #FOAvip English Wikipedia <ref>{{Cite pmid|26053515 }}</ref> Transdifferentiation of Fibroblasts by Defined Factors #MMPMID26053515 Zhao Z ; Xu M ; Wu M ; Tian X ; Zhang C ; Fu X Cell Reprogram 2015[Jun]; 17 (3 ): 151-9 PMID26053515 show ga Cellular differentiation is usually considered to be an irreversible process during development due to robust lineage commitment. Feedback and feed-forward loops play a significant role in maintaining lineage-specific gene expression processes in various cell types, and, in turn, factors secreted by cells may regulate the homeostatic balance of these cycles during development and differentiation. The output of biological responses is controlled by such mechanisms in many regulatory pathways through gene networks involved in transcription, RNA metabolism, signal transduction, micromolecular synthesis, and degradation. The pluripotent stage during cellular conversion may be avoided through ectopic expression of lineage-specific factors. Lineage-specific transcription factors produced during development may strengthen cell type-specific gene expression patterns. Cellular phenotypes are further stabilized by epigenetic modifications. This reprogramming approach could have important implications for disease modeling and regenerative and personalized medicine. |*Cell Transdifferentiation [MESH] |Animals [MESH] |Fibroblasts/*physiology [MESH] |Gene Expression Regulation [MESH] |Humans [MESH] |Signal Transduction [MESH]Transdifferentiation of Fibroblasts by Defined Factors (epmc).pdf DeepDyve Pubget Overpricing