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10.1038/nrg.2016.150 http://scihub22266oqcxt.onion/10.1038/nrg.2016.150 C5501165!5501165 !27990019     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27990019 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Rev+Genet 2017 ; 18 (3 ): 164-179 Nephropedia Template TP {{tp|p=27990019 |t=2017. Transcriptional architecture of the mammalian circadian clock |pdf=|usr=}}{{27990019 }} gab.com Text Transcriptional architecture of the mammalian circadian clock JO: Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=27990019 #FOAvip Circadian clocks are endogenous oscillators that control 24-hour physiological and behavioural processes in organisms. These cell-autonomous clocks are composed of a transcription-translation-based autoregulatory feedback loop. With the development of next-generation sequencing approaches, biochemical and genomic insights into circadian function have recently come into focus. Genome-wide analyses of the clock transcriptional feedback loop have revealed a global circadian regulation of processes such as transcription factor occupancy, RNA polymerase II recruitment and initiation, nascent transcription, and chromatin remodelling. The genomic targets of circadian clocks are pervasive and are intimately linked to the regulation of metabolism, cell growth and physiology. Twit Text FOAVip Transcriptional architecture of the mammalian circadian clock ????Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=27990019 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27990019 #FOAvip English Wikipedia <ref>{{Cite pmid|27990019 }}</ref> Transcriptional architecture of the mammalian circadian clock #MMPMID27990019 Takahashi JS Nat Rev Genet 2017[Mar]; 18 (3 ): 164-179 PMID27990019 show ga Circadian clocks are endogenous oscillators that control 24-hour physiological and behavioural processes in organisms. These cell-autonomous clocks are composed of a transcription-translation-based autoregulatory feedback loop. With the development of next-generation sequencing approaches, biochemical and genomic insights into circadian function have recently come into focus. Genome-wide analyses of the clock transcriptional feedback loop have revealed a global circadian regulation of processes such as transcription factor occupancy, RNA polymerase II recruitment and initiation, nascent transcription, and chromatin remodelling. The genomic targets of circadian clocks are pervasive and are intimately linked to the regulation of metabolism, cell growth and physiology. |*Epigenesis, Genetic [MESH] |*Transcription, Genetic [MESH] |Animals [MESH] |Chromatin Assembly and Disassembly/*genetics [MESH] |Circadian Clocks/*genetics [MESH] |Gene Expression Profiling [MESH] |Genome-Wide Association Study [MESH] |Humans [MESH] |Mammals/*genetics [MESH]Transcriptional architecture of the mammalian circadian clock (epmc).pdf DeepDyve Pubget Overpricing