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2017 ; 6
(2
): 192-198
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Traditional Chinese medical therapy for erectile dysfunction
#MMPMID28540226
Li H
; Jiang H
; Liu J
Transl Androl Urol
2017[Apr]; 6
(2
): 192-198
PMID28540226
show ga
Traditional Chinese medicine (TCM), including acupuncture and Chinese herbs, is
used as an alternative therapy to increase the curative effect for erectile
dysfunction (ED). A large number of studies have been conducted to investigate
the effect and mechanism of TCM for treating ED. The therapeutic effect of
acupuncture on ED is still controversial at present. However, some Chinese herbs
exhibited satisfying outcomes and they might improve erectile function by
activating nitric oxide synthase (NOS)-cyclic guanosine monophosphate (cGMP)
pathway, increasing cyclic adenosine monophosphate (cAMP) expression, elevating
testosterone level, reducing intracellular Ca(2+) concentration, down-regulating
transforming growth factor ?1 (TGF?1)/Smad2 signaling pathway, or ameliorating
the oxidative stress.