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10.15698/mic2017.01.553 http://scihub22266oqcxt.onion/10.15698/mic2017.01.553 C5354552!5354552!28357385     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28357385.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Microb+Cell ä ; 4 (1): 29-31 Nephropedia Template TP {{tp|p=28357385|t=ä. Toxin-mediated gene regulatory mechanism in Staphylococcus aureus |pdf=|usr=}}{{28357385}} gab.com Text Toxin-mediated gene regulatory mechanism in Staphylococcus aureus JO: Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357385 #FOAvip The dangerous human pathogen Staphylococcus aureus relies heavily on toxins to cause disease, but toxin production can put a strong burden on the bacteria?s energy balance. Thus, controlling the synthesis of proteins solely needed in times of toxin production represents a way for the bacteria to avoid wasting energy. One hypothetical manner to accomplish this sort of regulation is by gene regulatory functions of the toxins themselves. There have been several reports about gene regulation by toxins in S. aureus, but these were never verified on the molecular level. In our study published in MBio [Joo et al., 7(5). pii: e01579-16], we show that phenol-soluble modulins (PSMs), important peptide toxins of S. aureus, release a repressor from the promoter of the operon encoding the toxin export system, thereby enabling toxin secretion. This study describes the first molecular regulatory mechanism exerted by an S. aureus toxin, setting a paradigmatic example of how S. aureus toxins may influence cell functions to adjust them to times of toxin production. Twit Text FOAVip Toxin-mediated gene regulatory mechanism in Staphylococcus aureus ????Microb Cell http://www.kidney.de/pget.php?&tw=1&pmid=28357385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28357385 #FOAvip English Wikipedia <ref>{{Cite pmid|28357385}}</ref> Toxin-mediated gene regulatory mechanism in Staphylococcus aureus #MMPMID28357385 Joo HS; Otto M Microb Cell ä[]; 4 (1): 29-31 PMID28357385show ga The dangerous human pathogen Staphylococcus aureus relies heavily on toxins to cause disease, but toxin production can put a strong burden on the bacteria?s energy balance. Thus, controlling the synthesis of proteins solely needed in times of toxin production represents a way for the bacteria to avoid wasting energy. One hypothetical manner to accomplish this sort of regulation is by gene regulatory functions of the toxins themselves. There have been several reports about gene regulation by toxins in S. aureus, but these were never verified on the molecular level. In our study published in MBio [Joo et al., 7(5). pii: e01579-16], we show that phenol-soluble modulins (PSMs), important peptide toxins of S. aureus, release a repressor from the promoter of the operon encoding the toxin export system, thereby enabling toxin secretion. This study describes the first molecular regulatory mechanism exerted by an S. aureus toxin, setting a paradigmatic example of how S. aureus toxins may influence cell functions to adjust them to times of toxin production. äToxin-mediated gene regulatory mechanism in Staphylococcus aureus (epmc).pdf DeepDyve Pubget Overpricing