Towards the Physics of Calcium Signalling in Plants
#MMPMID27137393
Martins TV
; Evans MJ
; Woolfenden HC
; Morris RJ
Plants (Basel)
2013[Sep]; 2
(4
): 541-88
PMID27137393
show ga
Calcium is an abundant element with a wide variety of important roles within
cells. Calcium ions are inter- and intra-cellular messengers that are involved in
numerous signalling pathways. Fluctuating compartment-specific calcium ion
concentrations can lead to localised and even plant-wide oscillations that can
regulate downstream events. Understanding the mechanisms that give rise to these
complex patterns that vary both in space and time can be challenging, even in
cases for which individual components have been identified. Taking a systems
biology approach, mathematical and computational techniques can be employed to
produce models that recapitulate experimental observations and capture our
current understanding of the system. Useful models make novel predictions that
can be investigated and falsified experimentally. This review brings together
recent work on the modelling of calcium signalling in plants, from the scale of
ion channels through to plant-wide responses to external stimuli. Some in silico
results that have informed later experiments are highlighted.
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