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10.1042/BST20160085 http://scihub22266oqcxt.onion/10.1042/BST20160085 C5095900!5095900 !27911730     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27911730 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27911730 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biochem+Soc+Trans 2016 ; 44 (5 ): 1483-1490 Nephropedia Template TP {{tp|p=27911730 |t=2016. Toward a therapy for mitochondrial disease |pdf=|usr=}}{{27911730 }} gab.com Text Toward a therapy for mitochondrial disease JO: Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=27911730 #FOAvip Mitochondrial disorders are a group of genetic diseases affecting the energy-converting process of oxidative phosphorylation. The extreme variability of symptoms, organ involvement, and clinical course represent a challenge to the development of effective therapeutic interventions. However, new possibilities have recently been emerging from studies in model organisms and awaiting verification in humans. I will discuss here the most promising experimental approaches and the challenges we face to translate them into the clinics. The current clinical trials will also be briefly reviewed. Twit Text FOAVip Toward a therapy for mitochondrial disease ????Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=27911730 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27911730 #FOAvip English Wikipedia <ref>{{Cite pmid|27911730 }}</ref> Toward a therapy for mitochondrial disease #MMPMID27911730 Viscomi C Biochem Soc Trans 2016[Oct]; 44 (5 ): 1483-1490 PMID27911730 show ga Mitochondrial disorders are a group of genetic diseases affecting the energy-converting process of oxidative phosphorylation. The extreme variability of symptoms, organ involvement, and clinical course represent a challenge to the development of effective therapeutic interventions. However, new possibilities have recently been emerging from studies in model organisms and awaiting verification in humans. I will discuss here the most promising experimental approaches and the challenges we face to translate them into the clinics. The current clinical trials will also be briefly reviewed. |Animals [MESH] |Clinical Trials as Topic [MESH] |DNA, Mitochondrial/*genetics/metabolism [MESH] |Energy Metabolism/genetics [MESH] |Humans [MESH] |Mitochondria/*genetics/metabolism [MESH] |Mitochondrial Diseases/*genetics/metabolism/*therapy [MESH] |Outcome Assessment, Health Care [MESH] |Reactive Oxygen Species/metabolism [MESH]Toward a therapy for mitochondrial disease (epmc).pdf DeepDyve Pubget Overpricing