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2016 ; 49
(5
): 316-321
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Tomography patterns of lung disease in systemic sclerosis
#MMPMID27818546
Bastos AL
; Corrêa RA
; Ferreira GA
Radiol Bras
2016[Sep]; 49
(5
): 316-321
PMID27818546
show ga
Currently, lung impairment is the leading factor responsible for the morbidity
and mortality associated with systemic sclerosis. Therefore, the recognition of
the various tomography patterns becomes decisive in the clinical management of
these patients. In high-resolution computed tomography studies, the most common
pattern is that of nonspecific interstitial pneumonia. However, there are other
forms of lung involvement that must also be recognized. The aim of this study was
to review the literature on the main changes resulting from pulmonary involvement
in systemic sclerosis and the corresponding radiological findings, considering
the current classification of interstitial diseases. We searched the Medline
(PubMed), Lilacs, and SciELO databases in order to select articles related to
pulmonary changes in systemic sclerosis and published in English between 2000 and
2015. The pulmonary changes seen on computed tomography in systemic sclerosis are
varied and are divided into three main categories: interstitial, alveolar, and
vascular. Interstitial changes constitute the most common type of pulmonary
involvement in systemic sclerosis. However, alveolar and vascular manifestations
must also be recognized and considered in the presence of atypical clinical
presentations and inadequate treatment responses.