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10.1038/cmi.2014.52

http://scihub22266oqcxt.onion/10.1038/cmi.2014.52
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suck abstract from ncbi


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pmid25109681
      Cell+Mol+Immunol 2015 ; 12 (1 ): 24-30
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  • Tolerogenic dendritic cells and their applications in transplantation #MMPMID25109681
  • Li H ; Shi B
  • Cell Mol Immunol 2015[Jan]; 12 (1 ): 24-30 PMID25109681 show ga
  • In transplantation immunology, the ultimate goal is always to successfully and specifically induce immune tolerance of allografts. Tolerogenic dendritic cells (tol-DCs) with immunoregulatory functions have attracted much attention as they play important roles in inducing and maintaining immune tolerance. Here, we focused on tol-DCs that have the potential to promote immune tolerance after solid-organ transplantation. We focus on their development and interactions with other regulatory cells, and we also explore various tol-DC engineering protocols. Harnessing tol-DCs represents a promising cellular therapy for promoting long-term graft functional survival in transplant recipients that will most likely be achieved in the future.
  • |*Organ Transplantation [MESH]
  • |Animals [MESH]
  • |Cell Communication [MESH]
  • |Cell Differentiation [MESH]
  • |Dendritic Cells/*immunology/transplantation [MESH]
  • |Graft Rejection/etiology/*immunology/prevention & control [MESH]
  • |Graft Survival [MESH]
  • |Humans [MESH]
  • |Immunotherapy/*trends [MESH]
  • |Postoperative Complications/prevention & control [MESH]
  • |Transplantation Immunology [MESH]


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