Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26576197
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Comput+Math+Methods+Med
2015 ; 2015
(ä): 347273
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Time-Delayed Models of Gene Regulatory Networks
#MMPMID26576197
Parmar K
; Blyuss KB
; Kyrychko YN
; Hogan SJ
Comput Math Methods Med
2015[]; 2015
(ä): 347273
PMID26576197
show ga
We discuss different mathematical models of gene regulatory networks as relevant
to the onset and development of cancer. After discussion of alternative modelling
approaches, we use a paradigmatic two-gene network to focus on the role played by
time delays in the dynamics of gene regulatory networks. We contrast the dynamics
of the reduced model arising in the limit of fast mRNA dynamics with that of the
full model. The review concludes with the discussion of some open problems.