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10.1155/2015/347273

http://scihub22266oqcxt.onion/10.1155/2015/347273
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C4632181!4632181 !26576197
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suck abstract from ncbi


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pmid26576197
      Comput+Math+Methods+Med 2015 ; 2015 (ä): 347273
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  • Time-Delayed Models of Gene Regulatory Networks #MMPMID26576197
  • Parmar K ; Blyuss KB ; Kyrychko YN ; Hogan SJ
  • Comput Math Methods Med 2015[]; 2015 (ä): 347273 PMID26576197 show ga
  • We discuss different mathematical models of gene regulatory networks as relevant to the onset and development of cancer. After discussion of alternative modelling approaches, we use a paradigmatic two-gene network to focus on the role played by time delays in the dynamics of gene regulatory networks. We contrast the dynamics of the reduced model arising in the limit of fast mRNA dynamics with that of the full model. The review concludes with the discussion of some open problems.
  • |*Gene Regulatory Networks [MESH]
  • |*Models, Genetic [MESH]
  • |Computational Biology [MESH]
  • |Fuzzy Logic [MESH]
  • |Humans [MESH]
  • |Mathematical Concepts [MESH]
  • |Neoplasms/*genetics [MESH]
  • |Nonlinear Dynamics [MESH]
  • |RNA, Messenger/genetics [MESH]
  • |RNA, Neoplasm/genetics [MESH]
  • |Stochastic Processes [MESH]


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