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2017 ; 2017
(ä): 9454698
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Thyrotoxicosis and Choledocholithiasis Masquerading as Thyroid Storm
#MMPMID28912821
Horn CL
; Short PA
Case Rep Med
2017[]; 2017
(ä): 9454698
PMID28912821
show ga
A 26-year-old female, thirteen months postpartum, presented to the emergency
department for four weeks of epigastric abdominal pain, pruritus, new onset
jaundice, and 11.3?kgs (25?lbs) unintentional weight loss. On examination, she
was afebrile, tachycardic, alert, and oriented and had jaundice with scleral
icterus. Labs were significant for undetectable TSH, FT4 that was too high to
measure, and elevated total bilirubin, direct bilirubin, alkaline phosphatase,
and transaminases. Abdominal ultrasound revealed cholelithiasis without biliary
ductal dilation. Treatment for presumed thyroid storm was initiated. Further
work-up with magnetic resonance cholangiopancreatography (MRCP) revealed an
obstructing cholelith within the distal common bile duct. With the presence of
choledocholithiasis explaining the jaundice and abdominal pain, plus the absence
of CNS alterations, the diagnosis of thyroid storm was revised to thyrotoxicosis
complicated by choledocholithiasis. Endoscopic retrograde cholangiopancreatogram
(ERCP) with sphincterotomy was performed to alleviate the biliary obstruction,
with prompt symptomatic improvement. Thyroid storm is a rare manifestation of
hyperthyroidism with a high rate of morbidity and mortality. The diagnosis of
thyroid storm is based on clinical examination, and abnormal thyroid function
tests do not correlate with disease severity. Knowledge of the many
manifestations of thyroid storm will facilitate a quick and accurate diagnosis
and treatment.