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2014 ; 23
(3
): 161-6
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Thyroglossal duct remnant carcinoma: beyond the Sistrunk procedure
#MMPMID25056924
Carter Y
; Yeutter N
; Mazeh H
Surg Oncol
2014[Sep]; 23
(3
): 161-6
PMID25056924
show ga
Thyroglossal duct remnants (TGDRs) account for more than 70% of anterior neck
masses in children and 7% in adults; however, cancer is identified in only 1-2%
of the cases. The diagnosis of a TGDR is based on clinical manifestation of a
painless, anterior neck swelling, which elevates with swallowing. Cytological
evaluation with fine needle aspiration and biopsy (FNAB) may facilitate the
pre-operative diagnosis of malignancy, as the majority of TGDR cancers are of
papillary histotype. The recommended treatment for symptomatic TGDR without
evidence of malignancy is a Sistrunk procedure, which entails en bloc resection
of the remnant and the mid-portion of the hyoid bone. The optimal management of
patients with diagnosed malignancy is controversial, and in the past, additional
total thyroidectomy was recommended for all of these patients. The purpose of
this study is to review the literature on TGDR carcinomas, present the evidence
on the available diagnostic tools, identify the surgical and post-operative
medical management strategies, discuss current controversies, and conclude with a
management algorithm.