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2017 ; 49
(1
): 48-52
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Thymectomy in Myasthenia Gravis
#MMPMID28416933
Aydin Y
; Ulas AB
; Mutlu V
; Colak A
; Eroglu A
Eurasian J Med
2017[Feb]; 49
(1
): 48-52
PMID28416933
show ga
In recent years, thymectomy has become a widespread procedure in the treatment of
myasthenia gravis (MG). Likelihood of remission was highest in preoperative mild
disease classification (Osserman classification 1, 2A). In absence of thymoma or
hyperplasia, there was no relationship between age and gender in remission with
thymectomy. In MG treatment, randomized trials that compare conservative
treatment with thymectomy have started, recently. As with non-randomized trials,
remission with thymectomy in MG treatment was better than conservative treatment
with only medication. There are four major methods for the surgical approach:
transcervical, minimally invasive, transsternal, and combined transcervical
transsternal thymectomy. Transsternal approach with thymectomy is the accepted
standard surgical approach for many years. In recent years, the incidence of
thymectomy has been increasing with minimally invasive techniques using
thoracoscopic and robotic methods. There are not any randomized, controlled
studies which are comparing surgical techniques. However, when comparing
non-randomized trials, it is seen that minimally invasive thymectomy approaches
give similar results to more aggressive approaches.
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