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10.1074/jbc.R115.696468 http://scihub22266oqcxt.onion/10.1074/jbc.R115.696468 C4661373!4661373 !26453312     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26453312 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Biol+Chem 2015 ; 290 (48 ): 28594-5 Nephropedia Template TP {{tp|p=26453312 |t=2015. Thematic Minireview Series: Molecular Mechanisms of Synaptic Plasticity |pdf=|usr=}}{{26453312 }} gab.com Text Thematic Minireview Series: Molecular Mechanisms of Synaptic Plasticity JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26453312 #FOAvip The human brain contains ~86 billion neurons, which are precisely organized in specific brain regions and nuclei. High fidelity synaptic communication between subsets of neurons in specific circuits is required for most human behaviors, and is often disrupted in neuropsychiatric disorders. The presynaptic axon terminals of one neuron release neurotransmitters that activate receptors on multiple postsynaptic neuron targets to induce electrical and chemical responses. Typically, postsynaptic neurons integrate signals from multiple presynaptic neurons at thousands of synaptic inputs to control downstream communication to the next neuron in the circuit. Importantly, the strength (or efficiency) of signal transmission at each synapse can be modulated on time scales ranging up to the lifetime of the organism. This "synaptic plasticity" leads to changes in overall neuronal circuit activity, resulting in behavioral modifications. This series of minireviews will focus on recent advances in our understanding of the molecular and cellular mechanisms that control synaptic plasticity. Twit Text FOAVip Thematic Minireview Series: Molecular Mechanisms of Synaptic Plasticity ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=26453312 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26453312 #FOAvip English Wikipedia <ref>{{Cite pmid|26453312 }}</ref> Thematic Minireview Series: Molecular Mechanisms of Synaptic Plasticity #MMPMID26453312 Colbran RJ J Biol Chem 2015[Nov]; 290 (48 ): 28594-5 PMID26453312 show ga The human brain contains ~86 billion neurons, which are precisely organized in specific brain regions and nuclei. High fidelity synaptic communication between subsets of neurons in specific circuits is required for most human behaviors, and is often disrupted in neuropsychiatric disorders. The presynaptic axon terminals of one neuron release neurotransmitters that activate receptors on multiple postsynaptic neuron targets to induce electrical and chemical responses. Typically, postsynaptic neurons integrate signals from multiple presynaptic neurons at thousands of synaptic inputs to control downstream communication to the next neuron in the circuit. Importantly, the strength (or efficiency) of signal transmission at each synapse can be modulated on time scales ranging up to the lifetime of the organism. This "synaptic plasticity" leads to changes in overall neuronal circuit activity, resulting in behavioral modifications. This series of minireviews will focus on recent advances in our understanding of the molecular and cellular mechanisms that control synaptic plasticity. |*Nerve Net [MESH] |*Neuronal Plasticity [MESH] |Axons/*metabolism/pathology [MESH] |Humans [MESH] |Mental Disorders/*metabolism/pathology/physiopathology [MESH] |Neurotransmitter Agents/*metabolism [MESH]Thematic Minireview Series: Molecular Mechanisms of Synaptic Plasticit(epmc).pdf DeepDyve Pubget Overpricing