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10.1038/nrneurol.2015.13 http://scihub22266oqcxt.onion/10.1038/nrneurol.2015.13 C4664161!4664161 !25686754     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25686754 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25686754 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Rev+Neurol 2015 ; 11 (4 ): 192-208 Nephropedia Template TP {{tp|p=25686754 |t=2015. The role of inflammation in perinatal brain injury |pdf=|usr=}}{{25686754 }} gab.com Text The role of inflammation in perinatal brain injury JO: Nat Rev Neurol http://www.kidney.de/pget.php?&tw=1&pmid=25686754 #FOAvip Inflammation is increasingly recognized as being a critical contributor to both normal development and injury outcome in the immature brain. The focus of this Review is to highlight important differences in innate and adaptive immunity in immature versus adult brain, which support the notion that the consequences of inflammation will be entirely different depending on context and stage of CNS development. Perinatal brain injury can result from neonatal encephalopathy and perinatal arterial ischaemic stroke, usually at term, but also in preterm infants. Inflammation occurs before, during and after brain injury at term, and modulates vulnerability to and development of brain injury. Preterm birth, on the other hand, is often a result of exposure to inflammation at a very early developmental phase, which affects the brain not only during fetal life, but also over a protracted period of postnatal life in a neonatal intensive care setting, influencing critical phases of myelination and cortical plasticity. Neuroinflammation during the perinatal period can increase the risk of neurological and neuropsychiatric disease throughout childhood and adulthood, and is, therefore, of concern to the broader group of physicians who care for these individuals. Twit Text FOAVip The role of inflammation in perinatal brain injury ????Nat Rev Neurol http://www.kidney.de/pget.php?&tw=1&pmid=25686754 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25686754 #FOAvip English Wikipedia <ref>{{Cite pmid|25686754 }}</ref> The role of inflammation in perinatal brain injury #MMPMID25686754 Hagberg H ; Mallard C ; Ferriero DM ; Vannucci SJ ; Levison SW ; Vexler ZS ; Gressens P Nat Rev Neurol 2015[Apr]; 11 (4 ): 192-208 PMID25686754 show ga Inflammation is increasingly recognized as being a critical contributor to both normal development and injury outcome in the immature brain. The focus of this Review is to highlight important differences in innate and adaptive immunity in immature versus adult brain, which support the notion that the consequences of inflammation will be entirely different depending on context and stage of CNS development. Perinatal brain injury can result from neonatal encephalopathy and perinatal arterial ischaemic stroke, usually at term, but also in preterm infants. Inflammation occurs before, during and after brain injury at term, and modulates vulnerability to and development of brain injury. Preterm birth, on the other hand, is often a result of exposure to inflammation at a very early developmental phase, which affects the brain not only during fetal life, but also over a protracted period of postnatal life in a neonatal intensive care setting, influencing critical phases of myelination and cortical plasticity. Neuroinflammation during the perinatal period can increase the risk of neurological and neuropsychiatric disease throughout childhood and adulthood, and is, therefore, of concern to the broader group of physicians who care for these individuals. |*Adaptive Immunity [MESH] |*Immunity, Innate [MESH] |Animals [MESH] |Brain Injuries/complications/*immunology [MESH] |Brain/growth & development/*immunology [MESH] |Encephalitis/complications/*immunology [MESH] |Female [MESH] |Fetus [MESH] |Humans [MESH] |Infant, Newborn [MESH] |Inflammation Mediators/metabolism [MESH] |Pregnancy [MESH]The role of inflammation in perinatal brain injury (epmc).pdf DeepDyve Pubget Overpricing