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10.1186/s12944-015-0123-1

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suck abstract from ncbi


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pmid26415887
      Lipids+Health+Dis 2015 ; 14 (ä): 121
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  • The role of fatty acids in insulin resistance #MMPMID26415887
  • Sears B ; Perry M
  • Lipids Health Dis 2015[Sep]; 14 (ä): 121 PMID26415887 show ga
  • Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular basis for insulin resistance can be quite different in various organs. This review deals with various types of inflammatory inputs mediated by fatty acids, which affect the extent of insulin resistance in various organs.
  • |*Diet [MESH]
  • |*Insulin Resistance [MESH]
  • |Adipose Tissue/drug effects/metabolism/pathology [MESH]
  • |Dietary Fats/administration & dosage/*metabolism [MESH]
  • |Fatty Acids/administration & dosage/*metabolism [MESH]
  • |Gene Expression Regulation [MESH]
  • |Humans [MESH]
  • |Hypothalamus/drug effects/metabolism/pathology [MESH]
  • |I-kappa B Kinase/genetics/metabolism [MESH]
  • |Inflammation [MESH]
  • |Insulin/genetics/metabolism [MESH]
  • |Liver/drug effects/metabolism/pathology [MESH]
  • |MAP Kinase Kinase 4/genetics/metabolism [MESH]
  • |Muscle, Skeletal/drug effects/metabolism/pathology [MESH]
  • |Obesity/genetics/*metabolism/pathology [MESH]


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