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10.1016/j.chemphyslip.2016.05.003

http://scihub22266oqcxt.onion/10.1016/j.chemphyslip.2016.05.003
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suck abstract from ncbi


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pmid27179407
      Chem+Phys+Lipids 2016 ; 199 (ä): 136-143
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  • The role of cholesterol in membrane fusion #MMPMID27179407
  • Yang ST ; Kreutzberger AJB ; Lee J ; Kiessling V ; Tamm LK
  • Chem Phys Lipids 2016[Sep]; 199 (ä): 136-143 PMID27179407 show ga
  • Cholesterol modulates the bilayer structure of biological membranes in multiple ways. It changes the fluidity, thickness, compressibility, water penetration and intrinsic curvature of lipid bilayers. In multi-component lipid mixtures, cholesterol induces phase separations, partitions selectively between different coexisting lipid phases, and causes integral membrane proteins to respond by changing conformation or redistribution in the membrane. But, which of these often overlapping properties are important for membrane fusion?-Here we review a range of recent experiments that elucidate the multiple roles that cholesterol plays in SNARE-mediated and viral envelope glycoprotein-mediated membrane fusion.
  • |*Membrane Fusion [MESH]
  • |Animals [MESH]
  • |Cholesterol/*metabolism [MESH]
  • |Humans [MESH]
  • |Lipid Bilayers/metabolism [MESH]
  • |SNARE Proteins/metabolism [MESH]


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