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2015 ; 17
(1
): 7-14
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The potential roles of actin in the nucleus
#MMPMID25870830
Falahzadeh K
; Banaei-Esfahani A
; Shahhoseini M
Cell J
2015[Spr]; 17
(1
): 7-14
PMID25870830
show ga
Over the past few decades, actin's presence in the nucleus has been demonstrated.
Actin is a key protein necessary for different nuclear processes. Although actin
is well known for its functional role in dynamic behavior of the cytoskeleton,
emerging studies are now highlighting new roles for actin. At the present time
there is no doubt about the presence of actin in the nucleus. A number of studies
have uncovered the functional involvement of actin in nuclear processes. Actin as
one of the nuclear components has its own structured and functional rules, such
as nuclear matrix association, chromatin remodeling, transcription by RNA
polymerases I, II, III and mRNA processing. In this historical review, we attempt
to provide an overview of our current understanding of the functions of actin in
the nucleus.