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10.1038/nn.3917

http://scihub22266oqcxt.onion/10.1038/nn.3917
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C4889215!4889215 !25622573
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suck abstract from ncbi


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pmid25622573
      Nat+Neurosci 2015 ; 18 (2 ): 170-81
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  • The neocortical circuit: themes and variations #MMPMID25622573
  • Harris KD ; Shepherd GM
  • Nat Neurosci 2015[Feb]; 18 (2 ): 170-81 PMID25622573 show ga
  • Similarities in neocortical circuit organization across areas and species suggest a common strategy to process diverse types of information, including sensation from diverse modalities, motor control and higher cognitive processes. Cortical neurons belong to a small number of main classes. The properties of these classes, including their local and long-range connectivity, developmental history, gene expression, intrinsic physiology and in vivo activity patterns, are remarkably similar across areas. Each class contains subclasses; for a rapidly growing number of these, conserved patterns of input and output connections are also becoming evident. The ensemble of circuit connections constitutes a basic circuit pattern that appears to be repeated across neocortical areas, with area- and species-specific modifications. Such 'serially homologous' organization may adapt individual neocortical regions to the type of information each must process.
  • |Animals [MESH]
  • |Humans [MESH]
  • |Interneurons/*physiology [MESH]
  • |Neocortex/*cytology/physiology [MESH]


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