Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25622573
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
The neocortical circuit: themes and variations
#MMPMID25622573
Harris KD
; Shepherd GM
Nat Neurosci
2015[Feb]; 18
(2
): 170-81
PMID25622573
show ga
Similarities in neocortical circuit organization across areas and species suggest
a common strategy to process diverse types of information, including sensation
from diverse modalities, motor control and higher cognitive processes. Cortical
neurons belong to a small number of main classes. The properties of these
classes, including their local and long-range connectivity, developmental
history, gene expression, intrinsic physiology and in vivo activity patterns, are
remarkably similar across areas. Each class contains subclasses; for a rapidly
growing number of these, conserved patterns of input and output connections are
also becoming evident. The ensemble of circuit connections constitutes a basic
circuit pattern that appears to be repeated across neocortical areas, with area-
and species-specific modifications. Such 'serially homologous' organization may
adapt individual neocortical regions to the type of information each must
process.