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2016 ; 14
(1
): 188
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The inevitable colonisation of Singapore by Zika virus
#MMPMID27866470
Fisher D
; Cutter J
BMC Med
2016[Nov]; 14
(1
): 188
PMID27866470
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Singapore is endemic for Dengue virus, with approximately 10,000 to 20,000 annual
cases reported in recent years. In 2012, Chikungunya was introduced, although the
numbers of cases reported is much fewer. The current Zika virus pandemic
originating in Brazil represents a threat to all regions with Aedes mosquitoes,
particularly those well connected by travellers. In this respect, it was felt
inevitable that Singapore would eventually realise its third endemic flavivirus.
In late August 2016, a primary care practitioner observed a cluster of
geographically linked patients attending with fever and rash. This resulted in
the first identification of locally transmitted Zika in Singapore on August 27,
2016. This prompted a robust response in an attempt to stop further spread, which
continued for approximately 10 days until a large number of laboratory-confirmed
cases were found as a result of active case finding. Surprisingly, the strain was
later identified to be of Asian lineage and distinct from that originating in the
Americas, prompting speculation over the epidemiology of this under recognised
virus in Asia.
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