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10.1155/2015/795738 http://scihub22266oqcxt.onion/10.1155/2015/795738 C4449900!4449900 !26075261     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26075261 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biomed+Res+Int 2015 ; 2015 (ä): 795738 Nephropedia Template TP {{tp|p=26075261 |t=2015. The genetic and environmental factors for keratoconus |pdf=|usr=}}{{26075261 }} gab.com Text The genetic and environmental factors for keratoconus JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=26075261 #FOAvip Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone-shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It affects all ethnic groups and both genders. Both environmental and genetic factors may contribute to its pathogenesis. This review is to summarize the current research development in KC epidemiology and genetic etiology. Environmental factors include but are not limited to eye rubbing, atopy, sun exposure, and geography. Genetic discoveries have been reviewed with evidence from family-based linkage analysis and fine mapping in linkage region, genome-wide association studies, and candidate genes analyses. A number of genes have been discovered at a relatively rapid pace. The detailed molecular mechanism underlying KC pathogenesis will significantly advance our understanding of KC and promote the development of potential therapies. Twit Text FOAVip The genetic and environmental factors for keratoconus ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=26075261 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26075261 #FOAvip English Wikipedia <ref>{{Cite pmid|26075261 }}</ref> The genetic and environmental factors for keratoconus #MMPMID26075261 Gordon-Shaag A ; Millodot M ; Shneor E ; Liu Y Biomed Res Int 2015[]; 2015 (ä): 795738 PMID26075261 show ga Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone-shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It affects all ethnic groups and both genders. Both environmental and genetic factors may contribute to its pathogenesis. This review is to summarize the current research development in KC epidemiology and genetic etiology. Environmental factors include but are not limited to eye rubbing, atopy, sun exposure, and geography. Genetic discoveries have been reviewed with evidence from family-based linkage analysis and fine mapping in linkage region, genome-wide association studies, and candidate genes analyses. A number of genes have been discovered at a relatively rapid pace. The detailed molecular mechanism underlying KC pathogenesis will significantly advance our understanding of KC and promote the development of potential therapies. |*Genetic Linkage [MESH] |Astigmatism/etiology/genetics/pathology [MESH] |Environmental Exposure/*adverse effects [MESH] |Genome-Wide Association Study [MESH] |Humans [MESH] |Keratoconus/complications/*genetics/metabolism/pathology [MESH]The genetic and environmental factors for keratoconus (epmc).pdf DeepDyve Pubget Overpricing