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2015 ; 5
(ä): 15194
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The effect of enamel proteins on erosion
#MMPMID26468660
Baumann T
; Carvalho TS
; Lussi A
Sci Rep
2015[Oct]; 5
(ä): 15194
PMID26468660
show ga
Enamel proteins form a scaffold for growing hydroxyapatite crystals during enamel
formation. They are then almost completely degraded during enamel maturation,
resulting in a protein content of only 1% (w/v) in mature enamel. Nevertheless,
this small amount of remaining proteins has important effects on the mechanical
and structural properties of enamel and on the electrostatic properties of its
surface. To analyze how enamel proteins affect tooth erosion, human enamel
specimens were deproteinated. Surface microhardness (SMH), surface reflection
intensity (SRI) and calcium release of both deproteinated and control specimens
were monitored while continuously eroding them. The deproteination itself already
reduced the initial SMH and SRI of the enamel significantly (p?0.001 and
p?0.01). During the course of erosion, the progression of all three evaluated
parameters differed significantly between the two groups (p?0.001 for each).
The deproteinated enamel lost its SMH and SRI faster, and released more calcium
than the control group, but these differences were only significant at later
stages of erosion, where not only surface softening but surface loss can be
observed. We conclude that enamel proteins have a significant effect on erosion,
protecting the enamel and slowing down the progression of erosion when
irreversible surface loss starts to occur.