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10.1016/j.sbi.2015.04.002 http://scihub22266oqcxt.onion/10.1016/j.sbi.2015.04.002 C4476956!4476956 !26057099     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26057099 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Struct+Biol 2015 ; 31 (ä): 124-39 Nephropedia Template TP {{tp|p=26057099 |t=2015. The chromatin fiber: multiscale problems and approaches |pdf=|usr=}}{{26057099 }} gab.com Text The chromatin fiber: multiscale problems and approaches JO: Curr Opin Struct Biol http://www.kidney.de/pget.php?&tw=1&pmid=26057099 #FOAvip The structure of chromatin, affected by many factors from DNA linker lengths to posttranslational modifications, is crucial to the regulation of eukaryotic cells. Combined experimental and computational methods have led to new insights into its structural and dynamical features, from interactions due to the flexible core histone tails or linker histones to the physical mechanism driving the formation of chromosomal domains. Here we present a perspective of recent advances in chromatin modeling techniques at the atomic, mesoscopic, and chromosomal scales with a view toward developing multiscale computational strategies to integrate such findings. Innovative modeling methods that connect molecular to chromosomal scales are crucial for interpreting experiments and eventually deciphering the complex dynamic organization and function of chromatin in the cell. Twit Text FOAVip The chromatin fiber: multiscale problems and approaches ????Curr Opin Struct Biol http://www.kidney.de/pget.php?&tw=1&pmid=26057099 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26057099 #FOAvip English Wikipedia <ref>{{Cite pmid|26057099 }}</ref> The chromatin fiber: multiscale problems and approaches #MMPMID26057099 Ozer G ; Luque A ; Schlick T Curr Opin Struct Biol 2015[Apr]; 31 (ä): 124-39 PMID26057099 show ga The structure of chromatin, affected by many factors from DNA linker lengths to posttranslational modifications, is crucial to the regulation of eukaryotic cells. Combined experimental and computational methods have led to new insights into its structural and dynamical features, from interactions due to the flexible core histone tails or linker histones to the physical mechanism driving the formation of chromosomal domains. Here we present a perspective of recent advances in chromatin modeling techniques at the atomic, mesoscopic, and chromosomal scales with a view toward developing multiscale computational strategies to integrate such findings. Innovative modeling methods that connect molecular to chromosomal scales are crucial for interpreting experiments and eventually deciphering the complex dynamic organization and function of chromatin in the cell. |*Chromatin/chemistry/metabolism [MESH] |*Models, Molecular [MESH] |Animals [MESH] |Humans [MESH] |Nucleosomes/chemistry/metabolism [MESH]The chromatin fiber: multiscale problems and approaches (epmc).pdf DeepDyve Pubget Overpricing