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10.1002/biot.201300018 http://scihub22266oqcxt.onion/10.1002/biot.201300018 C4033574!4033574 !24124015     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24124015 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biotechnol+J 2013 ; 8 (12 ): 1379-95 Nephropedia Template TP {{tp|p=24124015 |t=2013. The centrality of RNA for engineering gene expression |pdf=|usr=}}{{24124015 }} gab.com Text The centrality of RNA for engineering gene expression JO: Biotechnol J http://www.kidney.de/pget.php?&tw=1&pmid=24124015 #FOAvip Synthetic biology holds promise as both a framework for rationally engineering biological systems and a way to revolutionize how we fundamentally understand them. Essential to realizing this promise is the development of strategies and tools to reliably and predictably control and characterize sophisticated patterns of gene expression. Here we review the role that RNA can play towards this goal and make a case for why this versatile, designable, and increasingly characterizable molecule is one of the most powerful substrates for engineering gene expression at our disposal. We discuss current natural and synthetic RNA regulators of gene expression acting at key points of control--transcription, mRNA degradation, and translation. We also consider RNA structural probing and computational RNA structure predication tools as a way to study RNA structure and ultimately function. Finally, we discuss how next-generation sequencing methods are being applied to the study of RNA and to the characterization of RNA's many properties throughout the cell. Twit Text FOAVip The centrality of RNA for engineering gene expression ????Biotechnol J http://www.kidney.de/pget.php?&tw=1&pmid=24124015 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24124015 #FOAvip English Wikipedia <ref>{{Cite pmid|24124015 }}</ref> The centrality of RNA for engineering gene expression #MMPMID24124015 Chappell J ; Takahashi MK ; Meyer S ; Loughrey D ; Watters KE ; Lucks J Biotechnol J 2013[Dec]; 8 (12 ): 1379-95 PMID24124015 show ga Synthetic biology holds promise as both a framework for rationally engineering biological systems and a way to revolutionize how we fundamentally understand them. Essential to realizing this promise is the development of strategies and tools to reliably and predictably control and characterize sophisticated patterns of gene expression. Here we review the role that RNA can play towards this goal and make a case for why this versatile, designable, and increasingly characterizable molecule is one of the most powerful substrates for engineering gene expression at our disposal. We discuss current natural and synthetic RNA regulators of gene expression acting at key points of control--transcription, mRNA degradation, and translation. We also consider RNA structural probing and computational RNA structure predication tools as a way to study RNA structure and ultimately function. Finally, we discuss how next-generation sequencing methods are being applied to the study of RNA and to the characterization of RNA's many properties throughout the cell. |*Gene Expression Regulation [MESH] |*RNA [MESH] |*Synthetic Biology [MESH]The centrality of RNA for engineering gene expression (epmc).pdf DeepDyve Pubget Overpricing