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2015 ; 22
(6
): 1148-52
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The center for expanded data annotation and retrieval
#MMPMID26112029
Musen MA
; Bean CA
; Cheung KH
; Dumontier M
; Durante KA
; Gevaert O
; Gonzalez-Beltran A
; Khatri P
; Kleinstein SH
; O'Connor MJ
; Pouliot Y
; Rocca-Serra P
; Sansone SA
; Wiser JA
J Am Med Inform Assoc
2015[Nov]; 22
(6
): 1148-52
PMID26112029
show ga
The Center for Expanded Data Annotation and Retrieval is studying the creation of
comprehensive and expressive metadata for biomedical datasets to facilitate data
discovery, data interpretation, and data reuse. We take advantage of emerging
community-based standard templates for describing different kinds of biomedical
datasets, and we investigate the use of computational techniques to help
investigators to assemble templates and to fill in their values. We are creating
a repository of metadata from which we plan to identify metadata patterns that
will drive predictive data entry when filling in metadata templates. The metadata
repository not only will capture annotations specified when experimental datasets
are initially created, but also will incorporate links to the published
literature, including secondary analyses and possible refinements or retractions
of experimental interpretations. By working initially with the Human Immunology
Project Consortium and the developers of the ImmPort data repository, we are
developing and evaluating an end-to-end solution to the problems of metadata
authoring and management that will generalize to other data-management
environments.