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2016 ; 34
(ä): 127-135
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The cell biology of late blight disease
#MMPMID27723513
Whisson SC
; Boevink PC
; Wang S
; Birch PR
Curr Opin Microbiol
2016[Dec]; 34
(ä): 127-135
PMID27723513
show ga
Late blight, caused by the oomycete Phytophthora infestans, is a major global
disease of potato and tomato. Cell biology is teaching us much about the
developmental stages associated with infection, especially the haustorium, which
is a site of intimate interaction and molecular exchange between pathogen and
host. Recent observations suggest a role for the plant endocytic cycle in
specific recruitment of host proteins to the Extra-Haustorial Membrane,
emphasising the unique nature of this membrane compartment. In addition, there
has been a strong focus on the activities of RXLR effectors, which are delivered
into plant cells to modulate and manipulate host processes. RXLR effectors
interact directly with diverse plant proteins at a range of subcellular locations
to promote disease.
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