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2016 ; 28
(1
): 72-9
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The benign mimickers of prostatic acinar adenocarcinoma
#MMPMID27041929
Xu Y
; Wang Y
; Zhou R
; Li H
; Cheng H
; Wang Z
; Zhang J
Chin J Cancer Res
2016[Feb]; 28
(1
): 72-9
PMID27041929
show ga
As the most frequent malignant histological subtype in prostatic cancer,
prostatic acinar adenocarcinoma (PAA) has a series of benign mimickers including
prostatic or non-prostatic lesions and normal structures, which may lead to an
erroneous diagnosis and inappropriate treatment. It is very important to be aware
of the existence of these mimickers and to recognize their histological features.
The differential diagnosis should be based on a comprehensive evaluation of
clinical history, histological structure, cytological morphology and the results
of immunohistochemistry (IHC) staining, rather than on single criteria (e.g., the
presence of prominent nucleoli or basal cell layer).