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10.1186/s12947-015-0040-5 http://scihub22266oqcxt.onion/10.1186/s12947-015-0040-5 C4696344!4696344 !26714887     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26714887 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cardiovasc+Ultrasound 2015 ; 13 (ä): 49 Nephropedia Template TP {{tp|p=26714887 |t=2015. The beneficial effects of TAVI in mitral insufficiency |pdf=|usr=}}{{26714887 }} gab.com Text The beneficial effects of TAVI in mitral insufficiency JO: Cardiovasc Ultrasound http://www.kidney.de/pget.php?&tw=1&pmid=26714887 #FOAvip BACKGROUND: Previous studies have suggested that concomitant mitral regurgitation (MR) is a risk factor for acute transcatheter aortic valve implantation (TAVI) failure, but may improve afterwards. Aim of this study was to assess the prevalence, clinical meaning and modifications of MR in patients undergoing TAVI. METHODS: In a retrospective, two-center (Potenza-San Carlo and Roma- San Camillo) study, from January 2010 to June 2014 we enrolled 165 consecutive patients (age =80?±?5 years, 74 males, Ejection Fraction 51?±?9 %) referred for TAVI with either Medtronic Core-ReValving System (in 114 patients, 69%) or balloon-expandable Edwards SAPIEN/SAPIEN XT (in 51 patients, 31%). All patients underwent TTE and TEE assessment of MR (from 1, mild to 4?=?severe according to ESC latest guidelines) with core lab reading by a single observer blinded to patient identity and status. Assessment was performed at baseline (24 h prior to intervention) and at 1, 6, 12 and 24 months. RESULTS: Mild-to-Moderate MR (grade 1-2) was present in 137 patients and Moderate-to-Severe MR (grade 3-4) was present in 28 patients. No significant differences were seen comparing perioperative mortality and morbidity between the two groups. In the group of preoperative MR grade 3-4 the mean decrease from MR pre-TAVI to MR at 1 month post-TAVI was 0.464 (p?<?0.0001) and this improvement was persistent at 6 months (p?<?0.0001) and at 12 months (p?<?0.0001), with partial benefit loss at 1 and 2 years. The mean difference from Left Atrial volume post-TAVI at 1 month was 16.5 ml (p?<?0.0001) and this improvement was persistent at 12 months 12.12 ml (p?<?0.0001). CONCLUSIONS: TAVI effectively treats the aortic valve but as a beneficial by product also ameliorates concomitant MR. The presence of moderate-to-severe MR does not increase the acute risk of failure of TAVI. In successful procedures, the MR improves immediately and persistently. Twit Text FOAVip The beneficial effects of TAVI in mitral insufficiency ????Cardiovasc Ultrasound http://www.kidney.de/pget.php?&tw=1&pmid=26714887 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26714887 #FOAvip English Wikipedia <ref>{{Cite pmid|26714887 }}</ref> The beneficial effects of TAVI in mitral insufficiency #MMPMID26714887 Costantino MF ; Dores E ; Innelli P ; Matera A ; Santillo V ; Violini R ; Fiorilli R ; Cappabianca G ; Marraudino N ; Picano E ; Tarsia G Cardiovasc Ultrasound 2015[Dec]; 13 (ä): 49 PMID26714887 show ga BACKGROUND: Previous studies have suggested that concomitant mitral regurgitation (MR) is a risk factor for acute transcatheter aortic valve implantation (TAVI) failure, but may improve afterwards. Aim of this study was to assess the prevalence, clinical meaning and modifications of MR in patients undergoing TAVI. METHODS: In a retrospective, two-center (Potenza-San Carlo and Roma- San Camillo) study, from January 2010 to June 2014 we enrolled 165 consecutive patients (age =80?±?5 years, 74 males, Ejection Fraction 51?±?9 %) referred for TAVI with either Medtronic Core-ReValving System (in 114 patients, 69%) or balloon-expandable Edwards SAPIEN/SAPIEN XT (in 51 patients, 31%). All patients underwent TTE and TEE assessment of MR (from 1, mild to 4?=?severe according to ESC latest guidelines) with core lab reading by a single observer blinded to patient identity and status. Assessment was performed at baseline (24 h prior to intervention) and at 1, 6, 12 and 24 months. RESULTS: Mild-to-Moderate MR (grade 1-2) was present in 137 patients and Moderate-to-Severe MR (grade 3-4) was present in 28 patients. No significant differences were seen comparing perioperative mortality and morbidity between the two groups. In the group of preoperative MR grade 3-4 the mean decrease from MR pre-TAVI to MR at 1 month post-TAVI was 0.464 (p? |Aged [MESH] |Aged, 80 and over [MESH] |Aortic Valve Stenosis/complications/diagnosis/*surgery [MESH] |Aortic Valve/*surgery [MESH] |Echocardiography [MESH] |Female [MESH] |Follow-Up Studies [MESH] |Humans [MESH] |Incidence [MESH] |Italy/epidemiology [MESH] |Male [MESH] |Mitral Valve Insufficiency/*complications/diagnosis/epidemiology [MESH] |Retrospective Studies [MESH] |Risk Assessment/*methods [MESH] |Severity of Illness Index [MESH] |Survival Rate/trends [MESH] |Time Factors [MESH] |Transcatheter Aortic Valve Replacement/*methods [MESH]The beneficial effects of TAVI in mitral insufficiency (epmc).pdf DeepDyve Pubget Overpricing