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2015 ; 11
(2
): 74-83
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The basics of intravascular optical coherence tomography
#MMPMID26161097
Roleder T
; J?ka?a J
; Ka?u?a GL
; Partyka ?
; Proniewska K
; Pociask E
; Zasada W
; Wojakowski W
; G?sior Z
; Dudek D
Postepy Kardiol Interwencyjnej
2015[]; 11
(2
): 74-83
PMID26161097
show ga
Optical coherence tomography (OCT) has opened new horizons for intravascular
coronary imaging. It utilizes near-infrared light to provide a microscopic
insight into the pathology of coronary arteries in vivo. Optical coherence
tomography is also capable of identifying the chemical composition of
atherosclerotic plaques and detecting traits of their vulnerability. At present
it is the only tool to measure the thickness of the fibrous cap covering the
lipid core of the atheroma, and thus it is an exceptional modality to detect
plaques that are prone to rupture (thin fibrous cap atheromas). Moreover, it
facilitates distinguishing between plaque rupture and plaque erosion as a cause
of acute intracoronary thrombosis. Optical coherence tomography is applied to
guide angioplasties of coronary lesions and to assess outcomes of percutaneous
coronary interventions broadly. It identifies stent malapposition, dissections,
and thrombosis with unprecedented precision. Furthermore, OCT helps to monitor
vessel healing after stenting. It evaluates the coverage of stent struts by the
neointima and detects in-stent neoatherosclerosis. With so much potential, new
studies are warranted to determine OCT's clinical impact. The following review
presents the technical background, basics of OCT image interpretation, and
practical tips for adequate OCT imaging, and outlines its established and
potential clinical application.