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The application of anticoagulant therapy to sepsis
#MMPMID28572981
Thachil J
; Iba T
J Intensive Care
2017[]; 5
(?): 32
PMID28572981
show ga
Since the withdrawal of recombinant-activated protein C, the anticoagulant
therapy for sepsis was taken no notice. For instance, the international sepsis
guidelines did not share a space for this therapy. However, we can see the signs
of change recently. The Surviving Sepsis Campaign Guidelines 2016 introduced the
development of recombinant thrombomodulin, and the European Society of Intensive
Care Medicine released comments on this subject. However, since small but
important discrepancy was recognized between the standpoints of Japan (more
aggressive) and other countries (rather conservative), we intend to discuss on
this point.