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2015 ; 26
(11
): 1814-9
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English Wikipedia
The SEQUEST family tree
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J Am Soc Mass Spectrom
2015[Nov]; 26
(11
): 1814-9
PMID26122518
show ga
Since its introduction in 1994, SEQUEST has gained many important new
capabilities, and a host of successor algorithms have built upon its successes.
This Account and Perspective maps the evolution of this important tool and charts
the relationships among contributions to the SEQUEST legacy. Many of the changes
represented improvements in computing speed by clusters and graphics cards. Mass
spectrometry innovations in mass accuracy and activation methods led to shifts in
fragment modeling and scoring strategies. These changes, as well as the movement
of laboratories and lab members, have led to great diversity among the members of
the SEQUEST family. Graphical Abstract ?.