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10.1016/j.tem.2017.03.002 http://scihub22266oqcxt.onion/10.1016/j.tem.2017.03.002 C5474130!5474130 !28410994     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28410994 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28410994 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Endocrinol+Metab 2017 ; 28 (7 ): 485-496 Nephropedia Template TP {{tp|p=28410994 |t=2017. The Role of Oxysterols in Human Cancer |pdf=|usr=}}{{28410994 }} gab.com Text The Role of Oxysterols in Human Cancer JO: Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=28410994 #FOAvip Oxysterols are oxygenated derivatives of cholesterol formed in the human body or ingested in the diet. By modulating the activity of many proteins [e.g., liver X receptors (LXRs), oxysterol-binding proteins (OSBPs), some ATP-binding cassette (ABC) transporters], oxysterols can affect many cellular functions and influence various physiological processes (e.g., cholesterol metabolism, membrane fluidity regulation, intracellular signaling pathways). Therefore, the role of oxysterols is also important in pathological conditions (e.g., atherosclerosis, diabetes mellitus type 2, neurodegenerative disorders). Finally, current evidence suggests that oxysterols play a role in malignancies such as breast, prostate, colon, and bile duct cancer. This review summarizes the physiological importance of oxysterols in the human body with a special emphasis on their roles in various tumors. Twit Text FOAVip The Role of Oxysterols in Human Cancer ????Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=28410994 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28410994 #FOAvip English Wikipedia <ref>{{Cite pmid|28410994 }}</ref> The Role of Oxysterols in Human Cancer #MMPMID28410994 Kloudova A ; Guengerich FP ; Soucek P Trends Endocrinol Metab 2017[Jul]; 28 (7 ): 485-496 PMID28410994 show ga Oxysterols are oxygenated derivatives of cholesterol formed in the human body or ingested in the diet. By modulating the activity of many proteins [e.g., liver X receptors (LXRs), oxysterol-binding proteins (OSBPs), some ATP-binding cassette (ABC) transporters], oxysterols can affect many cellular functions and influence various physiological processes (e.g., cholesterol metabolism, membrane fluidity regulation, intracellular signaling pathways). Therefore, the role of oxysterols is also important in pathological conditions (e.g., atherosclerosis, diabetes mellitus type 2, neurodegenerative disorders). Finally, current evidence suggests that oxysterols play a role in malignancies such as breast, prostate, colon, and bile duct cancer. This review summarizes the physiological importance of oxysterols in the human body with a special emphasis on their roles in various tumors. |Animals [MESH] |Cholesterol/metabolism [MESH] |Female [MESH] |Humans [MESH] |Hydroxycholesterols/*pharmacology [MESH] |Lipid Metabolism/drug effects [MESH] |Male [MESH] |Metabolic Networks and Pathways/drug effects [MESH]The Role of Oxysterols in Human Cancer (epmc).pdf DeepDyve Pubget Overpricing