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10.4137/CGast.S38203 http://scihub22266oqcxt.onion/10.4137/CGast.S38203 C4991576!4991576 !27656094     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27656094 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Med+Insights+Gastroenterol 2016 ; 9 (ä): 51-62 Nephropedia Template TP {{tp|p=27656094 |t=2016. The Role of Laboratory Tests in Crohn s Disease |pdf=|usr=}}{{27656094 }} gab.com Text The Role of Laboratory Tests in Crohn s Disease JO: Clin Med Insights Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=27656094 #FOAvip In the past, laboratory tests were considered of limited value in Crohn's disease (CD). In the era of biologics, laboratory tests have become essential to evaluate the inflammatory burden of the disease (C-reactive protein, fecal calprotectin) since symptoms-based scores are subjective, to predict the response to pharmacological options and the risk of relapse, to discriminate CD from ulcerative colitis, to select candidates to anti-tumor necrosis factors [screening tests looking for hepatitis B virus and hepatitis C virus status and latent tuberculosis], to assess the risk of adverse events (testing for thiopurine metabolites and thiopurine-methyltransferase activity), and to personalize and optimize therapy (therapeutic drug monitoring). Pharmacogenetics, though presently confined to the assessment of thiopurineme methyltransferase polymorphisms and hematological toxicity associated with thiopurine treatment, is a promising field that will contribute to a better understanding of the molecular mechanisms of the variability in response to the drugs used in CD with the attempt to expand personalized care and precision medicine strategies. Twit Text FOAVip The Role of Laboratory Tests in Crohn s Disease ????Clin Med Insights Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=27656094 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27656094 #FOAvip English Wikipedia <ref>{{Cite pmid|27656094 }}</ref> The Role of Laboratory Tests in Crohn s Disease #MMPMID27656094 Cappello M ; Morreale GC Clin Med Insights Gastroenterol 2016[]; 9 (ä): 51-62 PMID27656094 show ga In the past, laboratory tests were considered of limited value in Crohn's disease (CD). In the era of biologics, laboratory tests have become essential to evaluate the inflammatory burden of the disease (C-reactive protein, fecal calprotectin) since symptoms-based scores are subjective, to predict the response to pharmacological options and the risk of relapse, to discriminate CD from ulcerative colitis, to select candidates to anti-tumor necrosis factors [screening tests looking for hepatitis B virus and hepatitis C virus status and latent tuberculosis], to assess the risk of adverse events (testing for thiopurine metabolites and thiopurine-methyltransferase activity), and to personalize and optimize therapy (therapeutic drug monitoring). Pharmacogenetics, though presently confined to the assessment of thiopurineme methyltransferase polymorphisms and hematological toxicity associated with thiopurine treatment, is a promising field that will contribute to a better understanding of the molecular mechanisms of the variability in response to the drugs used in CD with the attempt to expand personalized care and precision medicine strategies. äThe Role of Laboratory Tests in Crohn s Disease (epmc).pdf DeepDyve Pubget Overpricing