The Role of Antibiotic Prophylaxis in Percutaneous Nephrolithotomy
#MMPMID27162507
Lai WS
; Assimos D
Rev Urol
2016[]; 18
(1
): 10-4
PMID27162507
show ga
Postoperative sepsis is the most common cause of mortality after percutaneous
nephrolithotomy (PCNL) procedures. Studies investigating the use of antibiotics
in PCNL patients have shown that prophylactic antibiotic regimens can reduce the
rate of postoperative infectious complications. In addition, several studies have
identified risk factors for sepsis development that can help guide antibiotic
treatment and perioperative care overall. This has led the American Urological
Association to recommend antibiotic prophylaxis for PCNL as a best practice
policy statement. However, despite prophylaxis, postoperative sepsis has
continued to remain the leading cause of mortality in PCNL patients. In addition,
multiple antibiotic protocols exist within the guideline realms. This review
assesses the development and role of antibiotic prophylaxis for PCNL procedures.