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2018 ; 113
(1
): 2
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The RISK pathway and beyond
#MMPMID29143177
Rossello X
; Yellon DM
Basic Res Cardiol
2018[Jan]; 113
(1
): 2
PMID29143177
show ga
Research on cardioprotection has attracted considerable attention during the past
30 years following the discovery of ischemic preconditioning with great advances
being made in the field, particularly in the description of the molecular
signalling behind this cardioprotective intervention. In a time when basic
research is struggling to translate its findings into therapies in the clinical
setting, this viewpoint has the intention of presenting to clinical and basic
scientists how the reperfusion injury salvage kinase pathway has been described
and dissected, as well as highlighting its relevance in cardioprotection.
|*Ischemic Preconditioning, Myocardial
[MESH]
|Animals
[MESH]
|Apoptosis
[MESH]
|Humans
[MESH]
|Myocardial Infarction/therapy
[MESH]
|Myocardial Reperfusion Injury/enzymology/*prevention & control
[MESH]