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2015 ; 2
(ä): 824-826
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The Q, Compound Q is Finally Deciphered
#MMPMID26346336
Bhagi-Damodaran A
; Lu Y
Inorg Chem Front
2015[]; 2
(ä): 824-826
PMID26346336
show ga
Methane monooxygenases (MMOs) activate the high energy C-H bond of methane and
convert it to methanol with high selectivity and under physiological conditions.
Despite decades of efforts focusing on elucidating the structure, function and
mechanism of soluble MMOs, the structure of a key intermediate (called compound
Q) remained unknown. This article highlights a recent report by Banerjee et. al.
which not only firmly establishes the core-structure of Q, but also provides
significant insight into its formation, reaction with methane and eventual decay.