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10.4161/23723556.2014.974467

http://scihub22266oqcxt.onion/10.4161/23723556.2014.974467
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suck abstract from ncbi


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pmid27308428
      Mol+Cell+Oncol 2015 ; 2 (2 ): e974467
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  • The PVT1-MYC duet in cancer #MMPMID27308428
  • Tseng YY ; Bagchi A
  • Mol Cell Oncol 2015[Apr]; 2 (2 ): e974467 PMID27308428 show ga
  • Gain of 8q24, harboring the avian myelocytomatosis viral oncogene homolog (MYC), is a frequent mutation in cancers. Although MYC is the usual suspect in these cancers, the role of other co-gained loci remains mostly unknown. We have recently found that MYC partners with the adjacent long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1), which stabilizes MYC protein and potentiates its activity.
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