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10.1186/s13326-016-0077-x http://scihub22266oqcxt.onion/10.1186/s13326-016-0077-x C4893294!4893294 !27259657     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27259657 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Biomed+Semantics 2016 ; 7 (1 ): 34 Nephropedia Template TP {{tp|p=27259657 |t=2016. The Orthology Ontology: development and applications |pdf=|usr=}}{{27259657 }} gab.com Text The Orthology Ontology: development and applications JO: J Biomed Semantics http://www.kidney.de/pget.php?&tw=1&pmid=27259657 #FOAvip BACKGROUND: Computational comparative analysis of multiple genomes provides valuable opportunities to biomedical research. In particular, orthology analysis can play a central role in comparative genomics; it guides establishing evolutionary relations among genes of organisms and allows functional inference of gene products. However, the wide variations in current orthology databases necessitate the research toward the shareability of the content that is generated by different tools and stored in different structures. Exchanging the content with other research communities requires making the meaning of the content explicit. DESCRIPTION: The need for a common ontology has led to the creation of the Orthology Ontology (ORTH) following the best practices in ontology construction. Here, we describe our model and major entities of the ontology that is implemented in the Web Ontology Language (OWL), followed by the assessment of the quality of the ontology and the application of the ORTH to existing orthology datasets. This shareable ontology enables the possibility to develop Linked Orthology Datasets and a meta-predictor of orthology through standardization for the representation of orthology databases. The ORTH is freely available in OWL format to all users at http://purl.org/net/orth . CONCLUSIONS: The Orthology Ontology can serve as a framework for the semantic standardization of orthology content and it will contribute to a better exploitation of orthology resources in biomedical research. The results demonstrate the feasibility of developing shareable datasets using this ontology. Further applications will maximize the usefulness of this ontology. Twit Text FOAVip The Orthology Ontology: development and applications ????J Biomed Semantics http://www.kidney.de/pget.php?&tw=1&pmid=27259657 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27259657 #FOAvip English Wikipedia <ref>{{Cite pmid|27259657 }}</ref> The Orthology Ontology: development and applications #MMPMID27259657 Fernández-Breis JT ; Chiba H ; Legaz-García Mdel C ; Uchiyama I J Biomed Semantics 2016[Jun]; 7 (1 ): 34 PMID27259657 show ga BACKGROUND: Computational comparative analysis of multiple genomes provides valuable opportunities to biomedical research. In particular, orthology analysis can play a central role in comparative genomics; it guides establishing evolutionary relations among genes of organisms and allows functional inference of gene products. However, the wide variations in current orthology databases necessitate the research toward the shareability of the content that is generated by different tools and stored in different structures. Exchanging the content with other research communities requires making the meaning of the content explicit. DESCRIPTION: The need for a common ontology has led to the creation of the Orthology Ontology (ORTH) following the best practices in ontology construction. Here, we describe our model and major entities of the ontology that is implemented in the Web Ontology Language (OWL), followed by the assessment of the quality of the ontology and the application of the ORTH to existing orthology datasets. This shareable ontology enables the possibility to develop Linked Orthology Datasets and a meta-predictor of orthology through standardization for the representation of orthology databases. The ORTH is freely available in OWL format to all users at http://purl.org/net/orth . CONCLUSIONS: The Orthology Ontology can serve as a framework for the semantic standardization of orthology content and it will contribute to a better exploitation of orthology resources in biomedical research. The results demonstrate the feasibility of developing shareable datasets using this ontology. Further applications will maximize the usefulness of this ontology. |*Gene Ontology [MESH] |Genomics/*methods/standards [MESH]The Orthology Ontology: development and applications (epmc).pdf DeepDyve Pubget Overpricing