The Importance of Magnesium in Clinical Healthcare
#MMPMID29093983
Schwalfenberg GK
; Genuis SJ
Scientifica (Cairo)
2017[]; 2017
(?): 4179326
PMID29093983
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The scientific literature provides extensive evidence of widespread magnesium
deficiency and the potential need for magnesium repletion in diverse medical
conditions. Magnesium is an essential element required as a cofactor for over 300
enzymatic reactions and is thus necessary for the biochemical functioning of
numerous metabolic pathways. Inadequate magnesium status may impair biochemical
processes dependent on sufficiency of this element. Emerging evidence confirms
that nearly two-thirds of the population in the western world is not achieving
the recommended daily allowance for magnesium, a deficiency problem contributing
to various health conditions. This review assesses available medical and
scientific literature on health issues related to magnesium. A traditional
integrated review format was utilized for this study. Level I evidence supports
the use of magnesium in the prevention and treatment of many common health
conditions including migraine headache, metabolic syndrome, diabetes,
hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, and various cardiac
arrhythmias. Magnesium may also be considered for prevention of renal calculi and
cataract formation, as an adjunct or treatment for depression, and as a
therapeutic intervention for many other health-related disorders. In clinical
practice, optimizing magnesium status through diet and supplementation appears to
be a safe, useful, and well-documented therapy for several medical conditions.
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