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10.1111/acer.13066 http://scihub22266oqcxt.onion/10.1111/acer.13066 C5125635!5125635 !27122355     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27122355 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27122355 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Alcohol+Clin+Exp+Res 2016 ; 40 (6 ): 1154-65 Nephropedia Template TP {{tp|p=27122355 |t=2016. The Genetics of Fetal Alcohol Spectrum Disorders |pdf=|usr=}}{{27122355 }} gab.com Text The Genetics of Fetal Alcohol Spectrum Disorders JO: Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=27122355 #FOAvip The term "fetal alcohol spectrum disorders" (FASD) defines the full range of ethanol (EtOH)-induced birth defects. Numerous variables influence the phenotypic outcomes of embryonic EtOH exposure. Among these variables, genetics appears to play an important role, yet our understanding of the genetic predisposition to FASD is still in its infancy. We review the current literature that relates to the genetics of FASD susceptibility and gene-EtOH interactions. Where possible, we comment on potential mechanisms of reported gene-EtOH interactions. Early indications of genetic sensitivity to FASD came from human and animal studies using twins or inbred strains, respectively. These analyses prompted searches for susceptibility loci involved in EtOH metabolism and analyses of candidate loci, based on phenotypes observed in FASD. More recently, genetic screens in animal models have provided an additional insight into the genetics of FASD. Understanding FASD requires that we understand the many factors influencing phenotypic outcome following embryonic EtOH exposure. We are gaining ground on understanding some of the genetics behind FASD, yet much work remains to be carried out. Coordinated analyses using human patients and animal models are likely to be highly fruitful in uncovering the genetics behind FASD. Twit Text FOAVip The Genetics of Fetal Alcohol Spectrum Disorders ????Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=27122355 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27122355 #FOAvip English Wikipedia <ref>{{Cite pmid|27122355 }}</ref> The Genetics of Fetal Alcohol Spectrum Disorders #MMPMID27122355 Eberhart JK ; Parnell SE Alcohol Clin Exp Res 2016[Jun]; 40 (6 ): 1154-65 PMID27122355 show ga The term "fetal alcohol spectrum disorders" (FASD) defines the full range of ethanol (EtOH)-induced birth defects. Numerous variables influence the phenotypic outcomes of embryonic EtOH exposure. Among these variables, genetics appears to play an important role, yet our understanding of the genetic predisposition to FASD is still in its infancy. We review the current literature that relates to the genetics of FASD susceptibility and gene-EtOH interactions. Where possible, we comment on potential mechanisms of reported gene-EtOH interactions. Early indications of genetic sensitivity to FASD came from human and animal studies using twins or inbred strains, respectively. These analyses prompted searches for susceptibility loci involved in EtOH metabolism and analyses of candidate loci, based on phenotypes observed in FASD. More recently, genetic screens in animal models have provided an additional insight into the genetics of FASD. Understanding FASD requires that we understand the many factors influencing phenotypic outcome following embryonic EtOH exposure. We are gaining ground on understanding some of the genetics behind FASD, yet much work remains to be carried out. Coordinated analyses using human patients and animal models are likely to be highly fruitful in uncovering the genetics behind FASD. |Animals [MESH] |Fetal Alcohol Spectrum Disorders/*genetics [MESH] |Genetic Predisposition to Disease/*genetics [MESH] |Humans [MESH]The Genetics of Fetal Alcohol Spectrum Disorders (epmc).pdf DeepDyve Pubget Overpricing