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10.3390/ijms161125990 http://scihub22266oqcxt.onion/10.3390/ijms161125990 C4661849!4661849 !26569220     free     free     free       Int+J+Mol+Sci 2015 ; 16 (11 ): 26797-812 Nephropedia Template TP {{tp|p=26569220 |t=2015. The Function of Autophagy in Neurodegenerative Diseases |pdf=|usr=}}{{26569220 }} gab.com Text The Function of Autophagy in Neurodegenerative Diseases JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26569220 #FOAvip Macroautophagy, hereafter referred to as autophagy, is a bulk degradation process performed by lysosomes in which aggregated and altered proteins as well as dysfunctional organelles are decomposed. Autophagy is a basic cellular process that maintains homeostasis and is crucial for postmitotic neurons. Thus, impaired autophagic processes in neurons lead to improper homeostasis and neurodegeneration. Recent studies have suggested that impairments of the autophagic process are associated with several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and static encephalopathy of childhood with neurodegeneration in adulthood. In this review, we focus on the recent findings regarding the autophagic process and the involvement of autophagy in neurodegenerative diseases. Twit Text FOAVip The Function of Autophagy in Neurodegenerative Diseases ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26569220 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26569220 #FOAvip English Wikipedia <ref>{{Cite pmid|26569220 }}</ref> The Function of Autophagy in Neurodegenerative Diseases #MMPMID26569220 Kiriyama Y ; Nochi H Int J Mol Sci 2015[Nov]; 16 (11 ): 26797-812 PMID26569220 show ga Macroautophagy, hereafter referred to as autophagy, is a bulk degradation process performed by lysosomes in which aggregated and altered proteins as well as dysfunctional organelles are decomposed. Autophagy is a basic cellular process that maintains homeostasis and is crucial for postmitotic neurons. Thus, impaired autophagic processes in neurons lead to improper homeostasis and neurodegeneration. Recent studies have suggested that impairments of the autophagic process are associated with several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and static encephalopathy of childhood with neurodegeneration in adulthood. In this review, we focus on the recent findings regarding the autophagic process and the involvement of autophagy in neurodegenerative diseases. |AMP-Activated Protein Kinases/genetics/metabolism [MESH] |Alzheimer Disease/*genetics/metabolism/pathology [MESH] |Amyotrophic Lateral Sclerosis/*genetics/metabolism/pathology [MESH] |Apoptosis Regulatory Proteins/genetics/metabolism [MESH] |Autophagy-Related Protein-1 Homolog [MESH] |Autophagy/*genetics [MESH] |Beclin-1 [MESH] |Gene Expression Regulation [MESH] |Humans [MESH] |Huntington Disease/*genetics/metabolism/pathology [MESH] |Intracellular Signaling Peptides and Proteins/genetics/metabolism [MESH] |Lysosomes/metabolism [MESH] |Mechanistic Target of Rapamycin Complex 1 [MESH] |Membrane Proteins/genetics/metabolism [MESH] |Multiprotein Complexes/genetics/metabolism [MESH] |Neurons/metabolism/pathology [MESH] |Parkinson Disease/*genetics/metabolism/pathology [MESH] |Protein Serine-Threonine Kinases/genetics/metabolism [MESH] |Signal Transduction [MESH]The Function of Autophagy in Neurodegenerative Diseases (epmc).pdf DeepDyve Pubget Overpricing